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The incidence of hyperthyroidism causes and symptomsThe majority of hyperthyroidism slow onset, also had acute onset of the disease, the incidence of about 31/10 million, more female, male and female ratio was 1 ∶4~ 6, there was a statistically in 495 hyperthyroid patients, 416 were female, 84%, male 79 cases, accounting for 16%. In each age group of onset can be from 20 to 40, the age of onset of the disease is more.甲状腺 The incidence of thyroid disease in various regions differ, Shanghai First Medical College of the Institute in 30760 hospitalized patients, thyroid disease 585 cases, including 203 cases with hyperthyroidism, accounted for 34.7%; the First Affiliated Hospital Zhongshan Medical College in 106581 hospitalized patients, thyroid disease in 2070 cases, including 851 cases with hyperthyroidism, 41.1%. Hyperthyroidism hyperthyroidism usually refers to diffuse toxic goiter, clinically the most common. The etiology and pathogenesis has not been fully 杭州是同济医院 elucidated, there are two doctrines:①thyrotropin secreting pituitary adenomas over doctrine, that the disease is the pituitary TSH secretion caused by too much, but through the determination of blood in patients with thyroid stimulating hormone low, thyrotropin releasing excitatory test no reaction can occur, pituitary gland hyperthyroidism and other facts negate the traditional doctrine. The immunity theory that thyrotoxicosis is an autoimmune disease, modern research shows: the disease is in a genetic basis, due to infection, trauma and stress factors and induced, which belongs to the suppression of T lymphocyte function caused by the defect of an organ specific autoimmune disease, and autoimmune thyroiditis autoimmune equal genus thyroid disease. There have been 204 cases of this disease survey, 60% of the patients have a family quality tendency. 杭州同济大学医院Hyperthyroidism has many etiologies, depending on the etiology, classification is as follows: ( 1) thyroid hyperthyroidism, divide again for: diffuse toxic goiter ( Graves disease ); multiple nodular goiter with a high functioning thyroid nodules; autonomy; thyroid cancer ( follicular thyroid carcinoma ); neonatal thyrotoxicosis hyperthyroidism; iodine; ( 2) pituitary hyperthyroid, divide again for : pituitary adenoma ( TSH tumor ) induced thyrotoxicosis; non pituitary tumor induced thyrotoxicosis ( pituitary TH resistance ); ( 3 ) the patients with tumor of hyperthyroidism, divide again for: chorionic epithelium carcinoma complicated with hyperthyroidism; hydatidiform mole with hyperthyroidism; lung cancer, digestive system ( stomach, colon pancreatic cancer complicated by hyperthyroidism, ); ( 4) ovarian goiter with hyperthyroidism ( 5) thyroiditis hyperthyroidism, divide again for: subacute thyroiditis; Hashimoto's thyroiditis; radiation thyroiditis; ( 6) drug induced hyperthyroidism in various diseases caused by hyperthyroidism, with diffuse toxic thyroid spleen was the most common. Endocrine system disease hyperthyroidism is the most common disease, by a variety of reasons cause, which diffuse goiter with hyperthyroidism are most common, accounting for all patients with hyperthyroidism from 88% to 90%, is usually said that the hyperthyroidism. Because this disease patients most at the same time have high metabolic disease and thyroid enlargement, called diffuse toxic goiter, also known as Graves disease. The so-called high metabolic syndrome is due to excessive secretion of human thyroid hormone synthesis, causing metabolic hyperactivity, leading to carbohydrate, protein metabolic disorder presents a series of syndrome. Because patients with increased metabolic heat production, heat dissipation, increased significantly, the patient often made heat sweating, fatigue, skin is warm and moist. As a result of increased consumption, hyperthyroidism appetite, but excessive intake can not meet the body of material consumption, can cause weight loss. Thyroid hormone promotes intestinal glucose absorption, accelerated glucose oxidation using and hepatic glycogenolysis, can result in impaired glucose tolerance or the exacerbation of diabetes mellitus. Due to lipolysis and oxidation of cholesterol synthesis and excretion,杭州同德医院甲亢专科 accelerated, so patients with blood cholesterol levels reduced. The clinical manifestations of the disease are complex and diverse, most slow onset, it is difficult to determine the date of onset, a small number of patients in the trauma or infection after acute onset of stress. The clinical manifestations of a disease, the severity of the difference is very big, the light can be confused with neurosis, some patients with arrhythmia, cachexia or myopathy, proptosis as the main performance. Clinical on female patients with thyroid enlargement is obvious, and male patients were females as light, female heart palpitations, emotional instability is more see, men eat easy hungry, wasting, weakness of typical. The disease typically presents as a thyroid hormone ( TH ) secretion caused by too much high metabolic syndrome, goiter and eye syndrome, and the visible spirit, nerve, muscle, skeletal, cardiovascular, reproductive, hematopoietic system symptoms. Attention should be paid to the elderly and children patients display atypical.
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